Bile support, made for what changed.
A delayed-release supplement formulated for life on a GLP-1 — or life without a gallbladder.
Two formulas. One mission.
- Third-party tested
- cGMP certified
- Patent pending
- Fully disclosed dosages
Supplements That Prove Themselves.
Built on validated science. Designed for noticeable digestive support.
Gallavance Bile Support
Two formulations. Every ingredient disclosed. Every dose shown. Research-informed. Third-party tested. cGMP-manufactured in the USA.
Explore Gallavance →From $64.99/mo Founding Member · Free Shipping · 30 Servings
We're not promising miracles.
”Why Gallavance exists.
We started Medisyn Labs because the supplement market wasn't built for the way modern medicine has changed people's bodies.
If you've had your gallbladder removed, your digestion isn't broken — it just works differently now. If you're taking a GLP-1 medication, gastric emptying tends to slow — and bile timing can shift with it. Gallavance is a delayed-release bile support supplement, formulated for the way digestion actually works for these populations. We're not promising miracles. We're offering thoughtfully formulated daily support, made transparent.
— Bryan
Founder, Medisyn Labs
Patent Pending
Third-Party Tested
cGMP Manufactured
Made in the USA
The Research
The Science.
Most supplements ask you to trust them. We'd rather show you the work. Here's what the research says about why bile support matters for people on GLP-1 medications and people without a gallbladder, and how Gallavance is formulated to address it.
1.
GLP-1 medications change digestive timing.
GLP-1 receptor agonists slow gastric emptying — the rate at which food moves from your stomach to your small intestine. This is well-documented across clinical trials.
A 2022 meta-analysis of 76 randomized controlled trials, published in JAMA Internal Medicine, found that GLP-1 medications are associated with a measurable increase in gallbladder-related events, particularly at weight-loss doses and with longer treatment durations.
He L, et al. JAMA Internal Medicine, 2022.
2.
Without a gallbladder, bile flow continues — but on a different schedule.
Approximately 600,000 to 700,000 cholecystectomies are performed annually in the United States. After gallbladder removal, the liver continues to produce bile, but it flows continuously into the small intestine rather than being released in coordinated response to fatty meals.
This is why post-cholecystectomy patients often consider supplemental bile support — particularly during meals containing fats.
Source: NIDDK
3.
Why delayed-release matters.
Conventional bile supplements are released in the stomach, where bile acids and stomach acids interact in ways that may affect how much reaches the small intestine — the place bile actually does its work.
Gallavance uses a delayed-release capsule designed to bypass the stomach and release in the small intestine, where bile support is positioned to be most useful for fat digestion.
Watch: Our Formulation Approach →Transparency
What we promise. What we don't.
Two columns. No fine print. Read both.
What we promise
- Third-party tested for purity and potency, every batch
- Manufactured in a cGMP-certified, FDA-registered facility
- Patent-pending delayed-release formulation
- Two formulas, one for each dietary preference
- Honest education in plain language
- AI-disclosed marketing — we tell you when we use AI tools
What we don't promise
- That Gallavance treats, cures, or prevents any disease (because legally, no supplement can)
- That it works the same way for everyone (because individual digestion varies)
- Overnight results (because daily wellness is the work of weeks and months, not hours)
- A guaranteed timeline (because every body responds at its own pace)
- That it replaces conversations with your doctor (because we make supplements; your doctor makes medical decisions)
FAQ
Questions, answered.
Real answers to what people ask before they buy. If yours isn't here, we'd rather you ask than guess — reach us at support@medisynlabs.com.
Can I take Gallavance with my GLP-1 medication?
Always consult your doctor about supplements alongside prescription medications. Gallavance is a dietary supplement and is not a substitute for medical guidance.
What's the difference between Gallavance Original and Plant-Based?
Gallavance Original includes ox bile extract as its primary bile-derived component, along with phosphatidylcholine and botanical ingredients commonly used in digestive formulations. Gallavance Plant-Based is a bile-free option that uses microbial enzymes, phospholipids, and botanical ingredients for those who prefer a non-animal-derived formulation. Both formulations use delayed-release capsules designed to release in the small intestine.
How is delayed-release different from regular capsules?
DRcaps® are delayed-release capsules developed by Lonza. They are designed to resist stomach acid and release contents in the intestine under typical digestive conditions.
Who might consider Gallavance?
Gallavance may be considered by adults seeking a bile-inclusive or bile-free digestive formulation for use with meals containing fats. Individual needs and preferences vary. Consult your healthcare provider to determine whether it fits your routine.
Is there a subscription option?
Yes. Founding Members get a 5-year price guarantee, available only to the first 500 subscribers. Your monthly rate is locked at the lower of $64.99 or $10 off our one-time purchase price — whichever is less. If our one-time price rises, Founders stay at $64.99. If our one-time price drops, Founders save $10 off the new price. After Founding Member spots are filled, standard subscriptions are $67.49/month.
Science & Transparency
We explain the research. We disclose the sourcing. Every product page links to supporting science and third-party verification.
Start with our guide: How Bile Works in Fat Digestion.
Gallavance Is Just The Beginning
We're building a portfolio of supplements for underserved needs — conditions where current options fall short and where people can actually assess whether a product is helping them. Gallavance is our first formulation. It won't be our last.
Want early access to future formulations?