Understanding the Science Behind Bile Supplements

Ingredients in Gallavance: Background Information

This page lists the ingredients in Gallavance and gives background information about them. Ingredient background is separate from any claim about the finished product. Gallavance is a dietary supplement.

About the Ingredients

  • Ox bile extract: Gallavance Original contains ox bile extract (bovine-derived), which contains bile acids. Gallavance Plant-Based contains no ox bile.
  • Phosphatidylcholine (soybean-derived): Phosphatidylcholine is a phospholipid, and about 95% of the phospholipids secreted in bile are phosphatidylcholine (see reference below). Per three-capsule serving, Gallavance Original contains 600 mg, and Gallavance Plant-Based contains 650 mg, of an ingredient standardized to at least 35% phosphatidylcholine. Both Gallavance formulas use soybean-derived phosphatidylcholine and contain soy. Do not use if you have a soy allergy. Sunflower lecithin is a separate ingredient.
  • Capsules: Gallavance is supplied in DRcaps® HPMC delayed-release capsules designed to slow capsule opening. We make no claim about where in the body, or how quickly, ingredients are released.
  • Botanical extracts: Gallavance contains artichoke, dandelion root and ginger extracts. Amounts are listed in the Supplement Facts panel for each product.

Science Library — Deep-Dive Pages

Explore individual ingredient research and delivery science:

Selected References

Background references on bile physiology and GLP-1 medications. Listing a reference does not mean Gallavance has been shown to produce any result, and none of these studies tested Gallavance.

Bile Acid Physiology & Enterohepatic Circulation

  • Hofmann AF. "The enterohepatic circulation of bile acids in mammals: form and functions." Front Biosci (Landmark Ed). 2009;14:2584-2598. PMID: 19273221
  • Stellaard F, Lütjohann D. "Dynamics of the enterohepatic circulation of bile acids in healthy humans." Am J Physiol Gastrointest Liver Physiol. 2021;321(1):G55-G66. PMID: 33978477
  • Ferrebee CB, Dawson PA. "Metabolic effects of intestinal absorption and enterohepatic cycling of bile acids." Acta Pharm Sin B. 2015;5(2):129-134. PMID: 26579438

Phosphatidylcholine in Bile

  • van Berge Henegouwen GP, van der Werf SD, Ruben AT. "Fatty acid composition of phospholipids in bile in man: promoting effect of deoxycholate on arachidonate." Clin Chim Acta. 1987;165(1):27-37. PMID: 3111757. The abstract states that 95% of phospholipids in bile are secreted as phosphatidylcholine.

GLP-1 Medications & Gastric Emptying

  • Hiramoto B et al. "Quantified metrics of gastric emptying delay by glucagon-like peptide-1 agonists: a systematic review and meta-analysis with insights for periprocedural management." Am J Gastroenterol. 2024;119(6):1126-1140. PMID: 38634551

This reference list is not exhaustive. These references are provided for educational context only. They do not show that Gallavance, or any ingredient at the amounts in Gallavance, produces any health effect.

This page provides an educational overview of bile physiology,
fat emulsification, and the delivery system design behind
Gallavance™ formulations.

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.